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Gene Expression Data
Assay Details
Assay
Reference: J:68524 Ross S, et al., Selective expression of murine prostate stem cell antigen in fetal and adult tissues and the transgenic adenocarcinoma of the mouse prostate model of prostate carcinogenesis. Am J Pathol. 2001 Mar;158(3):809-16
Assay type: RNA in situ
MGI Accession ID: MGI:4422034
Gene symbol: Psca
Gene name: prostate stem cell antigen
Probe: Psca cDNA1
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Assay notes: 4% Formalin was used as a fixative. The authors state that there were no overt differences in pattern or level of expression between the CD-1 and C57BL/6 mouse strains.
Results
Specimen Not shown E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Absent

Specimen Not shown E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: urogenital sinus Present Regionally restricted Expression is in the epithelial lining of the urogenital sinus.

Specimen Not shown E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: skin Present

Specimen 1A,B: embryonic day 14.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS22: epithelium of urogenital sinus Strong 1A , 1B

Specimen 1C,D: embryonic day 14.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS22: epidermis Present 1D , 1C

Specimen 1E,F: embryonic day 17.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS25: esophagus epithelium Very strong Regionally restricted 1E , 1F Expression is in the squamous epithelium, absent in basal cells.
TS25: intestine epithelium Present Regionally restricted 1E , 1F Expression is in the mucosal epithelium of the gastrointestinal tract.
TS25: oral cavity Present 1F , 1E

Specimen 1G,H: embryonic day 17.5 (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS25: anal canal epithelium Strong Regionally restricted 1H , 1G Expression is in the transitional squamous portions of the anal canal in the superficial cell layers, and is absent in basally located epithelial cells.
TS25: colon epithelium Strong 1H , 1G

Specimen 2A,B: postnatal adult (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS28: prostate epithelium Present Regionally restricted 2B , 2A Expression is in secretory cells of the prostate, absent in basal cells.
TS28: prostate gland Strong Regionally restricted 2A , 2B Expression is at the juncture between the large prostatic ducts and the urethra.
TS28: urethra Strong Regionally restricted 2A , 2B Expression is at the juncture between the large prostatic ducts and the urethra.

Specimen 2C,D: postnatal adult (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS28: bladder mucosa Strong Regionally restricted 2D , 2C Expression is in superficial epithelial cells of the transitional cell mucosa of the urinary bladder. Basally located epithelial cells are negative or express low levels.
TS28: ureter Strong Regionally restricted 2D , 2C Expression is in the transitional cell mucosa.
TS28: urethra Strong Regionally restricted 2D , 2C Expression is in the transitional cell mucosa.

Specimen 2E,F: postnatal adult (more )
Note: Brightfield/darkfield pair.
Structure Level Pattern Image Note
TS28: renal pelvis Present Regionally restricted 2E , 2F Expression is in the epithelial lining.
TS28: renal papilla Present Regionally restricted 2F , 2E Expression is in scattered tubular epithelial cells of the collecting ducts of the renal papilla.
TS28: glomerular tuft Absent 2F , 2E
TS28: renal cortex Absent 2F , 2E

Specimen Not shown, male: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ductus deferens Absent
TS28: seminal vesicle Absent
TS28: skin Absent
TS28: testis Absent

Specimen Not shown, female: postnatal adult (more )
Structure Level Pattern Image Note
TS28: ureter Strong Regionally restricted Expression is in the transitional cell mucosa.
TS28: bladder mucosa Strong Regionally restricted Expression is in superficial epithelial cells of the transitional cell mucosa of the urinary bladder. Basally located epithelial cells are negative or express low levels.
TS28: renal pelvis Present Regionally restricted Expression is in the epithelial lining and in scattered tubular epithelial cells of the collecting ducts of the renal papilla.
TS28: glomerular tuft Absent
TS28: mammary gland Absent
TS28: renal cortex Absent
TS28: skin Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory