Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Ebf2-EGFP/icre)1Ggc
Name:	transgene insertion 1, Giacomo Consalez
MGI ID:	MGI:4421668
Synonyms:	Ebf2-Cre, Ebf2::Cre, Ebf2-iCre, Tg(Ebf2-Egfp-icre)1Ggc
Transgene:	Tg(Ebf2-EGFP/icre)1Ggc  Location: unknown
Alliance:	Tg(Ebf2-EGFP/icre)1Ggc page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Recombinase, Reporter) Mutation:    Insertion   Tg(Ebf2-EGFP/icre)1Ggc expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Ebf2 (MGI:894332)   Mutation details: The BAC clone RP24-283N8 containing 32 kb of 5'flanking sequence plus the first 6 exons of the murine Ebf2 gene was modified to insert the cDNA encoding a fusion of EGFP and the improved cre recombinase (icre) followed by the SV40 polyA signal into the first coding exon of Ebf2. This modified BAC was microinjected into the pronuclei of FVB/N oocytes. Founders were isolated and a line was established. The icre transcript distribution recapitulates that of endogenous Ebf2 transcripts at all locations and stages assayed. (J:156632)

Activity:	Tissue activity of this recombinase allele
Driver:	Ebf2 (mouse) Summary of all recombinase alleles driven by Ebf2. Comparative matrix view of recombinase activities Alliance mouse Ebf2 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:156632 Chung SH, et al., Purkinje cell phenotype restricts the distribution of unipolar brush cells. Neuroscience. 2009 Dec 29;164(4):1496-508
All:	4 reference(s)