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Foxp1tm1.1Pwt
Targeted Allele Detail
Summary
Symbol: Foxp1tm1.1Pwt
Name: forkhead box P1; targeted mutation 1.1, Philip W Tucker
MGI ID: MGI:4421653
Synonyms: Foxp1f
Gene: Foxp1  Location: Chr6:98902299-99499682 bp, - strand  Genetic Position: Chr6, 45.74 cM, cytoband E1
Alliance: Foxp1tm1.1Pwt page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:156832
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn frt flanked neo cassette with a 3' loxP site was inserted upstream of exon 11 and an additional loxP site was inserted downstream of exon 12. Flp mediated recombination removed the neo cassette leaving exons 11 and 12 floxed. (J:156832)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxp1 Mutation:  75 strains or lines available
References
Original:  J:156832 Feng X, et al., Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development. Blood. 2010 Jan 21;115(3):510-8
All:  35 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory