Summary | Transgene origin | Transgene description | Find Mice (IMSR) | Notes | References

Symbol:	Tg(Gxp5-TAg)2Mpo
Name:	transgene insertion 2, Matti Poutanen
MGI ID:	MGI:2448153
Synonyms:	GXP5-Tag2
Transgene:	Tg(Gxp5-TAg)2Mpo  Location: unknown
Alliance:	Tg(Gxp5-TAg)2Mpo page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Mutation details: Sequence encoding the SV40 large and small T antigens was adjoined to a 5 kb promoter fragment of murine Gxp5 (-5012 through +24). The murine Gxp5 promoter drove transgenic expression in the epididymis. Weak expression was also identified in the vas deferenes, seminal vesicles, and testes by RT-PCR analysis. (J:79658)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:79658 Sipila P, et al., Epididymal dysfunction initiated by the expression of simian virus 40 T-antigen leads to angulated sperm flagella and infertility in transgenic mice. Mol Endocrinol. 2002 Nov;16(11):2603-17
All:	1 reference(s)