Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(INS-NP)6171Mvh
Name:	transgene insertion 6171, Matthias von Herrath
MGI ID:	MGI:4420440
Synonyms:	Ins-LCMV-NP, LCMV-NP
Transgene:	Tg(INS-NP)6171Mvh  Location: unknown
Alliance:	Tg(INS-NP)6171Mvh page

Strain of Origin:

NOD/ShiLt

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Mutation details: The transgene expresses the complete cDNA from Armstrong's clone 53b of the lymphocytic choriomeningitis virus, LCMV, nucleoprotein, NP, regulated by human insulin promoter, INS. A Hepatitis B Virus polyadenylation signal as a terminator of transcription was fused downstream of the LCMV-NP. This transgene was microinjected into NOD/ShiLt oocytes and founder line 6171 was maintained on the NOD/ShiLt background. (J:122080)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:122080 Martinic MM, et al., Minimal impact of a de novo-expressed beta-cell autoantigen on spontaneous diabetes development in NOD mice. Diabetes. 2007 Apr;56(4):1059-68
All:	2 reference(s)