Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Camk2a-tTA)1Stl
Name:	transgene insertion 1, Susumu Tonegawa
MGI ID:	MGI:4418554
Synonyms:	alphaCamKII-loxP-STOP-loxP-tTA, Tg2
Transgene:	Tg(Camk2a-tTA)1Stl  Location: unknown
Alliance:	Tg(Camk2a-tTA)1Stl page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Transactivator) Mutation:    Insertion   Mutation details: The transgene construct contained the tetracycline transactivator (tTA) coding sequence downstream of a loxP-STOP-loxP fragement. This was inserted downstream of the alpha-CamKII (Camk2a) promoter in the final construct. Pronuclei of fertilized C57BL/6 eggs were injected with the purified linearized construct. A founder line 1 was established by backcrossing the founder with C57BL/6 mice. (J:131852)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:131852 Nakashiba T, et al., Transgenic inhibition of synaptic transmission reveals role of CA3 output in hippocampal learning. Science. 2008 Feb 29;319(5867):1260-4
All:	5 reference(s)