Tg(ACTB-TIMP1)1Werb
Transgene Detail
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| Symbol: |
Tg(ACTB-TIMP1)1Werb |
| Name: |
transgene insertion 1, Zena Werb |
| MGI ID: |
MGI:4418045 |
| Transgene: |
Tg(ACTB-TIMP1)1Werb Location: unknown
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| Alliance: |
Tg(ACTB-TIMP1)1Werb page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(ACTB-TIMP1)1Werb expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
TIMP1 (7076) |
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Mutation details: The human beta actin promoter was used to drive expression of a human cDNA construct located between the promoter and the beta actin 3' UTR. Human TIMP1 protein is present in the serum of transgenic mice at levels up to 50ng/ml.
(J:155924)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:155924 Alexander CM, et al., Rescue of mammary epithelial cell apoptosis and entactin degradation by a tissue inhibitor of metalloproteinases-1 transgene. J Cell Biol. 1996 Dec;135(6 Pt 1):1669-77 |
| All: |
1 reference(s) |
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