Tg(CD2-Tcra,-Tcrb)75Bucy
Transgene Detail
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| Symbol: |
Tg(CD2-Tcra,-Tcrb)75Bucy |
| Name: |
transgene insertion 75, R Pat Bucy |
| MGI ID: |
MGI:4417822 |
| Synonyms: |
TCR75 |
| Transgene: |
Tg(CD2-Tcra,-Tcrb)75Bucy Location: unknown
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| Alliance: |
Tg(CD2-Tcra,-Tcrb)75Bucy page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CD2-Tcra,-Tcrb)75Bucy expresses
2 genes
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Mutation details: This transgene results from the coinjection of two constructs derived from CD4+ T cell clones that react with the Kd54-68/I-Ab epitope. The Tcra construct uses V alpha 1.1 and J alpha 33. The Tcrb construct uses V beta 8.3 (current symbol Trbv13-1) and J beta 1.4. Both constructs are under the control of the human CD2 promoter.
(J:155849)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:155849 Honjo K, et al., CD4+ T-cell receptor transgenic T cells alone can reject vascularized heart transplants through the indirect pathway of alloantigen recognition. Transplantation. 2004 Feb 15;77(3):452-5 |
| All: |
21 reference(s) |
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Analysis Tools
