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Tg(CD2-Tcra,-Tcrb)34Bucy
Transgene Detail
Summary
Symbol: Tg(CD2-Tcra,-Tcrb)34Bucy
Name: transgene insertion 34, R Pat Bucy
MGI ID: MGI:4417821
Synonyms: TCR34
Transgene: Tg(CD2-Tcra,-Tcrb)34Bucy  Location: unknown  
Alliance: Tg(CD2-Tcra,-Tcrb)34Bucy page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CD2-Tcra,-Tcrb)34Bucy expresses 2 genes
 
Mutation detailsThis transgene results from the coinjection of two constructs derived from CD4+ T cell clones that react with the Kd54-68/I-Ab epitope. The Tcra construct uses V alpha 11.2 and J alpha 25. The Tcrb construct uses V beta 13 and J beta 1.6. Both constructs are under the control of the human CD2 promoter. (J:155849)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:155849 Honjo K, et al., CD4+ T-cell receptor transgenic T cells alone can reject vascularized heart transplants through the indirect pathway of alloantigen recognition. Transplantation. 2004 Feb 15;77(3):452-5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory