Tg(CD2-Tcra,-Tcrb)34Bucy
Transgene Detail
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Symbol: |
Tg(CD2-Tcra,-Tcrb)34Bucy |
Name: |
transgene insertion 34, R Pat Bucy |
MGI ID: |
MGI:4417821 |
Synonyms: |
TCR34 |
Transgene: |
Tg(CD2-Tcra,-Tcrb)34Bucy Location: unknown
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Alliance: |
Tg(CD2-Tcra,-Tcrb)34Bucy page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(CD2-Tcra,-Tcrb)34Bucy expresses
2 genes
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Mutation details: This transgene results from the coinjection of two constructs derived from CD4+ T cell clones that react with the Kd54-68/I-Ab epitope. The Tcra construct uses V alpha 11.2 and J alpha 25. The Tcrb construct uses V beta 13 and J beta 1.6. Both constructs are under the control of the human CD2 promoter.
(J:155849)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:155849 Honjo K, et al., CD4+ T-cell receptor transgenic T cells alone can reject vascularized heart transplants through the indirect pathway of alloantigen recognition. Transplantation. 2004 Feb 15;77(3):452-5 |
All: |
1 reference(s) |
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