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Tg(Hmgcr-lacZ)1Dym
Transgene Detail
Summary
Symbol: Tg(Hmgcr-lacZ)1Dym
Name: transgene insertion 1, Susan M Dymecki
MGI ID: MGI:4398965
Synonyms: Hmgcr::FRTZ
Transgene: Tg(Hmgcr-lacZ)1Dym  Location: unknown  
Alliance: Tg(Hmgcr-lacZ)1Dym page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe construct consists of 4.5 kb of the mouse Hmgcr promoter/enhancer sequences driving a lacZ reporter sequence with a nuclear localization signal. The reporter is disrupted by an FRT-flanked neo cassette. Flp recombinase-mediated recombination results in restoration of the lacZ transcript. (J:78660)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:78660 Rodriguez CI, et al., High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP. Nat Genet. 2000 Jun;25(2):139-40
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory