Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Sox2-cre/ERT2)1Skn
Name:	transgene insertion 1, Silvia K Nicolis
MGI ID:	MGI:4397776
Synonyms:	Sox2-creERT2
Transgene:	Tg(Sox2-cre/ERT2)1Skn  Location: unknown
Alliance:	Tg(Sox2-cre/ERT2)1Skn page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Sox2-cre/ERT2)1Skn expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Sox2   Mutation details: 5.7 kb of the 5' telencephalic enhancer/promoter was used to drive inducible, telencephalic-specific expression of a cre/estrogen receptor (ERT2) fusion. Six lines were created and the one with the most efficient activity was used in subsequent experiments. (J:154650)

Activity:	Tissue activity of this recombinase allele
Driver:	Sox2 (species not specified) Summary of all recombinase alleles driven by Sox2. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:154650 Favaro R, et al., Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh. Nat Neurosci. 2009 Oct;12(10):1248-56
All:	3 reference(s)