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Gene Expression Data
Assay Details
Assay
Reference: J:146657 Witte F, et al., Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expr Patterns. 2009 Apr;9(4):215-23
Assay type: RNA in situ
MGI Accession ID: MGI:4397448
Gene symbol: Ccn4
Gene name: cellular communication network factor 4
Probe: MGC clone 60506
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2F,f: embryonic day 13.5 (more )
Note: (f) is a higher magnification of the boxed area in (F).
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted 2F , 2f Expression is in the distal mesenchyme.
TS21: forelimb interdigital region mesenchyme Present 2F , 2f
TS21: hand Present Regionally restricted 2F , 2f Expression is in joint cells.

Specimen 2G,g,g': embryonic day 15.5 (more )
Note: (g,g') are higher magnifications of the boxed areas in (G).
Structure Level Pattern Image Note
TS23: forelimb skeleton Present Regionally restricted 2g' , 2g , 2G Expression is in perichondrium and periosteum.
TS23: forelimb mesenchyme Present Regionally restricted 2G , 2g , 2g' Expression is in joints.

Specimen Not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud Absent

Specimen S7 E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: somite Present S7_Wisp1 E10.5
TS17: forelimb bud Absent S7_Wisp1 E10.5

Specimen S7 E11.5: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud mesenchyme Present S7_Wisp1 E11.5

Specimen S7 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present S7_Wisp1 E12.5

Specimen S7 E13.5 WM: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present S7_Wisp1 E13.5

Specimen S7 E13.5 sxn: embryonic day 13.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted S7_Wisp1 E13.5 vibratome Expression is dorsal and ventral to the digit condensations.

Specimen S7 E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present Regionally restricted S7_Wisp1 E13.5 paraffin Expression is in the distal mesenchyme anterior to the cartilage condensations.
TS21: forelimb interdigital region mesenchyme Present S7_Wisp1 E13.5 paraffin
TS21: hand joint Present S7_Wisp1 E13.5 paraffin

Specimen S7 E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb skeleton Present S7_Wisp1 E15.5 Expression is in perichondrium and periosteum.
TS23: forelimb mesenchyme Present S7_Wisp1 E15.5


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory