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Gene Expression Data
Assay Details
Assay
Reference: J:146657 Witte F, et al., Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expr Patterns. 2009 Apr;9(4):215-23
Assay type: RNA in situ
MGI Accession ID: MGI:4367899
Gene symbol: Wnt4
Gene name: wingless-type MMTV integration site family, member 4
Probe: Wnt4 cDNA6
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1B WM: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud ectoderm Present 1B

Specimen 1b sxn: embryonic day 10.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS17: forelimb bud ectoderm Present 1b

Specimen 1C WM: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb interdigital region mesenchyme Present Regionally restricted 1C Expression is in the peripheral interdigital mesoderm.

Specimen 1c sxn: embryonic day 13.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS21: forelimb interdigital region mesenchyme Present Regionally restricted 1c Expression is in the peripheral interdigital mesoderm.
TS21: hand mesenchyme Present Regionally restricted 1c Expression is in mesenchyme surrounding blood vessels.

Specimen 1c': embryonic day 13.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS21: forelimb interdigital region mesenchyme Present Regionally restricted 1c' Expression is in the peripheral interdigital mesoderm.

Specimen 1D,d: embryonic day 15.5 (more )
Note: (d) is a higher magnification of the boxed area in (D).
Structure Level Pattern Image Note
TS23: forelimb epidermis Present Regionally restricted 1d , 1D Expression is in the basal cell layer.

Specimen S2 9.5 WM: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: forelimb bud ectoderm Strong S2_Wnt4 E9.5

Specimen S2 9.5 sxn: embryonic day 9.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS15: forelimb bud ectoderm Strong S2_Wnt4 E9.5 vibratome

Specimen S2 10.5 WM: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud ectoderm Strong S2_Wnt4 E10.5

Specimen S2 10.5 sxn: embryonic day 10.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS17: forelimb bud ectoderm Strong S2_Wnt4 E10.5 vibratome

Specimen S2 11.5 WM: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud ectoderm Present Graded S2_Wnt4 E11.5 Expression decreased distally.
TS19: forelimb bud mesenchyme Absent S2_Wnt4 E11.5

Specimen S2 11.5 sxn: embryonic day 11.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS19: forelimb bud ectoderm Present Graded S2_Wnt4 E11.5 vibratome Expression decreased distally.
TS19: forelimb bud mesenchyme Absent S2_Wnt4 E11.5 vibratome

Specimen S2 12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand epithelium Present S2_Wnt4 E12.5

Specimen S2 13.5 WM: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present S2_Wnt4 E13.5 Expression is in synovial joints.

Specimen S2 13.5 sxn: embryonic day 13.5 (more )
Note: Vibratome section
Structure Level Pattern Image Note
TS21: hand mesenchyme Present S2_Wnt4 E13.5 vibratome

Specimen S2 13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hand mesenchyme Present S2_Wnt4 E13.5 paraffin Expression is in synovial joints.

Specimen S2 15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forelimb epidermis Present Regionally restricted S2_Wnt4 E15.5 Expression is in basal cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory