Tg(Pomc-cre)5Brn
Transgene Detail
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| Symbol: |
Tg(Pomc-cre)5Brn |
| Name: |
transgene insertion 5, Anton Berns |
| MGI ID: |
MGI:4367779 |
| Synonyms: |
Tg(Pomc1-cre)1Brn, Tg(Pomc-cre)1Brn, Tg(PomcCre)5Brn |
| Transgene: |
Tg(Pomc-cre)5Brn Location: unknown
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| Alliance: |
Tg(Pomc-cre)5Brn page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Pomc-cre)5Brn expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Pomc |
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Mutation details: This transgene contains 706 base pairs of 5' flanking sequence containing the promoter of the rat pro-opiomelanocortin gene followed by the coding sequence for Cre recombinase with an amino-terminal nuclear localization signal (nlsCre), a synthetic intron, and SV40 splice and polyadenylation signals. Progeny of mice bearing this transgene crossed to lacZ Cre reporter mice exhibited large numbers of X-gal staining cells in the intermediate lobe and lesser staining in the anterior lobe of the pituitary gland.
(J:80158)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Pomc
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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This is one of six transgenic lines generated.
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| Original: |
J:80158 Akagi K, et al., Cre-mediated somatic site-specific recombination in mice. Nucleic Acids Res. 1997 May 1;25(9):1766-73 |
| All: |
4 reference(s) |
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