Gt(ROSA)26Sortm1(CAG-ECFP/Venus)Kgwa
Targeted Allele Detail
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Symbol: |
Gt(ROSA)26Sortm1(CAG-ECFP/Venus)Kgwa |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Osami Kanagawa |
MGI ID: |
MGI:4366503 |
Synonyms: |
Gt(ROSA)26Sortm1Kgwa, ROSA-lox-stop-lox-SCAT3.1 |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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Alliance: |
Gt(ROSA)26Sortm1(CAG-ECFP/Venus)Kgwa page
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Germline Transmission: |
Earliest citation of germline transmission:
J:153768
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
(C57BL/6 x DBA/2)F1
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Allele Type: |
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Targeted (Conditional ready, Reporter) |
Mutation: |
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Insertion
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Mutation details: The CAG-driven SCAT3.1 (caspase-3-sensitive fusion protein) with an upstream floxed STOP cassette was inserted into the locus. SCAT3.1 contains a fusion of ECFP and the Venus EYFP analog connected by a caspase 3 cleavable peptide. Removal of the floxed STOP cassette is required for the expression of the caspase-3-sensitive reporter fusion.
(J:153768)
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Original: |
J:153768 Tomura M, et al., Time-lapse observation of cellular function with fluorescent probe reveals novel CTL-target cell interactions. Int Immunol. 2009 Oct;21(10):1145-50 |
All: |
1 reference(s) |
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