Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hmgn3tm1.1Mbus
Name:	high mobility group nucleosomal binding domain 3; targeted mutation 1.1, Michael Bustin
MGI ID:	MGI:4366463
Gene:	Hmgn3  Location: Chr9:82992001-83028738 bp, - strand  Genetic Position: Chr9, 45.29 cM, cytoband E3.1
Alliance:	Hmgn3tm1.1Mbus page

Germline Transmission:	Earliest citation of germline transmission: J:153774
Parent Cell Line:	v6.4 (ES Cell)
Strain of Origin:	(C57BL/6J x 129S4/SvJae)F1

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 3, and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Germ line, flp mediated recombination removed the neo cassette leaving exons 3 and 4 floxed. (J:153774)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hmgn3 Mutation:	14 strains or lines available

Original:	J:153774 Ueda T, et al., The nucleosome binding protein HMGN3 modulates the transcription profile of pancreatic beta cells and affects insulin secretion. Mol Cell Biol. 2009 Oct;29(19):5264-76
All:	1 reference(s)