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Slc30a8tm1Geno
Targeted Allele Detail
Summary
Symbol: Slc30a8tm1Geno
Name: solute carrier family 30 (zinc transporter), member 8; targeted mutation 1, Genoway
MGI ID: MGI:4362060
Synonyms: ZnT8fl
Gene: Slc30a8  Location: Chr15:52158949-52199194 bp, + strand  Genetic Position: Chr15, 19.88 cM
Alliance: Slc30a8tm1Geno page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153253
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1 and an frt-flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. (J:153253)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc30a8 Mutation:  22 strains or lines available
References
Original:  J:153253 Lemaire K, et al., Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice. Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory