Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nrcam20884
Name:	neuronal cell adhesion molecule; 20884
MGI ID:	MGI:4361555
Gene:	Nrcam  Location: Chr12:44375668-44648747 bp, + strand  Genetic Position: Chr12, 20.71 cM
Alliance:	Nrcam20884 page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: A C to T transition is located in exon 36 resulting in a premature stop codon (Q1033X). Semiquantitative PCR analysis indicates a decrease in mRNA levels. Western blot and immunohistochemical analysis failed to detect protein in homozygotes. (J:153042) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nrcam Mutation:	87 strains or lines available

Original:	J:153042 Douglas DS, et al., Concurrent Lpin1 and Nrcam mouse mutations result in severe peripheral neuropathy with transitory hindlimb paralysis. J Neurosci. 2009 Sep 30;29(39):12089-100
All:	2 reference(s)