|
Results
|
Specimen
1A:
embryonic day 14.5
(more  )
Specimen
1A:
(close  )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1B:
embryonic day 18.5
(more )
Specimen
1B:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 18.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1C:
postnatal day 10
(more )
Specimen
1C:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 10
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1D:
embryonic day 14.5
(more )
Specimen
1D:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: main olfactory bulb |
Present |
Regionally restricted |
1D
|
Expression is in the mitral cells and glomerular cells.
|
Specimen
1E:
embryonic day 18.5
(more )
Specimen
1E:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 18.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: main olfactory bulb |
Present |
Regionally restricted |
1E
|
Expression is in the mitral cells and glomerular cells.
|
Specimen
1F:
postnatal day 10
(more )
Specimen
1F:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 10
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1G:
postnatal adult
(more )
Specimen
1G:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1H:
embryonic day 12.5
(more )
Specimen
1H:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1I:
embryonic day 14.5
(more )
Specimen
1I:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1J:
embryonic day 16.5
(more )
Specimen
1J:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1K:
postnatal day 0
(more )
Specimen
1K:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1L:
postnatal adult
(more )
Specimen
1L:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1M:
embryonic day 14.5
(more )
Specimen
1M:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1N:
embryonic day 16.5
(more )
Specimen
1N:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: hippocampus |
Present |
Regionally restricted |
1N
|
Expression is also in precursor cells of the dentate gyrus.
|
Specimen
1O:
postnatal day 0
(more )
Specimen
1O:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1P:
postnatal day 15
(more )
Specimen
1P:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1Q:
postnatal day 21
(more )
Specimen
1Q:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 21
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1R:
postnatal day 10
(more )
Specimen
1R:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 10
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
1S:
postnatal adult
(more )
Specimen
1S:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2A:
embryonic day 14.5
(more )
Specimen
2A:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2B:
embryonic day 16.5
(more )
Specimen
2B:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2C:
postnatal day 0
(more )
Specimen
2C:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2D:
postnatal day 15
(more )
Specimen
2D:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2E:
embryonic day 12.5
(more )
Specimen
2E:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: ganglionic eminence |
Strong |
Regionally restricted |
2E
|
Expression is in the rostral migratory pathway.
|
Specimen
2F:
embryonic day 16.5
(more )
Specimen
2F:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2G:
postnatal day 0
(more )
Specimen
2G:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2H:
postnatal day 21
(more )
Specimen
2H:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 21
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2I:
postnatal adult
(more )
Specimen
2I:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2J:
postnatal adult
(more )
Specimen
2J:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
2K:
postnatal adult
(more )
Specimen
2K:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
3A:
embryonic day 14.5
(more )
Specimen
3A:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
3B:
embryonic day 18.5
(more )
Specimen
3B:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 18.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: brainstem |
Present |
Regionally restricted |
3B
|
Expression is in the external granule layer and in the Purkinje layer.
|
| TS26: cerebellum |
Present |
Regionally restricted |
3B
|
Expression is in the external granule layer and in the Purkinje layer.
|
| TS26: periaqueductal grey |
Present |
|
3B
|
|
Specimen
3C:
postnatal day 15
(more )
Specimen
3C:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
3D:
postnatal day 15
(more )
Specimen
3D:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
3E:
postnatal adult
(more )
Specimen
3E:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
3F:
embryonic day 14.5
(more )
Specimen
3F:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: brainstem |
Present |
Regionally restricted |
3F
|
Expression is in the floor plate and vestibulocochlear nuclei.
|
Specimen
3G:
embryonic day 16.5
(more )
Specimen
3G:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: pons |
Present |
Regionally restricted |
3G
|
Expression is in the pontine migratory stream and the spinotrigeminal nuclei.
|
Specimen
3H:
embryonic day 18.5
(more )
Specimen
3H:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 18.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: pons |
Present |
Regionally restricted |
3H
|
Expression is in solitary, vestibular, and dorsal motor nuclei.
|
Specimen
3I:
postnatal day 15
(more )
Specimen
3I:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
3J:
embryonic day 14.5
(more )
Specimen
3J:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
3K:
embryonic day 16.5
(more )
Specimen
3K:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
3L:
postnatal day 10
(more )
Specimen
3L:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 10
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
3M:
postnatal adult
(more )
Specimen
3M:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 E10:
embryonic day 10.5
(more )
Specimen
Table 1 E10:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 10.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 E12:
embryonic day 12.5
(more )
Specimen
Table 1 E12:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 12.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: telencephalon |
Weak |
Regionally restricted |
|
Expression is in the olfactory ventricle and the cingulate and retrospinal cortex.
|
| TS20: cerebral cortex |
Weak |
Regionally restricted |
|
Expression is in the preplate.
|
| TS20: cerebral cortex ventricular layer |
Weak |
|
|
|
| TS20: forebrain |
Weak |
Regionally restricted |
|
Expression is in the hippocampus primordium and is very low in the fimbria/fornix. Expression is weak in medial septum, and very weak in the amygdaloid complex.
|
| TS20: diencephalon |
Strong |
Regionally restricted |
|
Expression is in the subcomissural organ.
|
| TS20: thalamus |
Weak |
Non-Uniform |
|
Expression is weak in the medial thalamus and is very weak in the dorsal, ventral, and lateral thalamus.
|
| TS20: hypothalamus |
Weak |
Regionally restricted |
|
Expression is in dorsal and arcuate nuclei.
|
| TS20: cerebellum primordium |
Weak |
Regionally restricted |
|
Expression is in the upper and lower rhombic lip and vey weak in deep nuclei.
|
| TS20: brainstem |
Weak |
Regionally restricted |
|
Expression is in the floor plate, facial nucleus, spinal trigeminal nucleus, reticular formation, and solitary nucleus.
|
| TS20: ganglionic eminence |
Moderate |
|
|
|
Specimen
Table 1 E14:
embryonic day 14.5
(more )
Specimen
Table 1 E14:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 14.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS22: main olfactory bulb |
Strong |
Non-Uniform |
|
Expression is in the olfactory ventricle and mitral cell layer and is weak in the glomerular cell layer.
|
| TS22: telencephalon |
Weak |
Regionally restricted |
|
Expression is in the piriform cortex and the cingulate and retrospinal cortex.
|
| TS22: hippocampus |
Weak |
Non-Uniform |
|
Expression is very weak in the fimbria/fornix.
|
| TS22: cerebral cortex ventricular layer |
Weak |
|
|
|
| TS22: cortical plate |
Weak |
|
|
|
| TS22: ganglionic eminence |
Strong |
|
|
|
| TS22: diencephalon |
Very strong |
Regionally restricted |
|
Expression is in the subcomissural organ.
|
| TS22: basal forebrain |
Moderate |
Regionally restricted |
|
Expression is moderate in the medial septum and amygdaloid complex, weak in caudate-putamen, globus pallidus, and the accumbens nucleus.
|
| TS22: basal ganglia |
Moderate |
Regionally restricted |
|
Expression is moderate in the medial septum and amygdaloid complex, weak in caudate-putamen, globus pallidus, and the accumbens nucleus.
|
| TS22: hypothalamus |
Strong |
Regionally restricted |
|
Expression is in the arcuate nuclei, moderate in the dorsal and paraventricular nuclei, and is very weak in the ventral nuclei.
|
| TS22: cerebellum |
Strong |
Regionally restricted |
|
Expression is in the upper rhombic lip, weak in the external germinative layer, and is very weak in the deep nuclei.
|
| TS22: hindbrain |
Strong |
Regionally restricted |
|
Expression is in the upper rhombic lip, weak in the external germinative layer, and is very weak in the deep nuclei.
|
| TS22: brainstem |
Strong |
Regionally restricted |
|
Expression is very strong the floor plate, strong in lower rhombic lip, pontine migratory stream, moderate in cochlear nuclei, weak in facial nucleus, spinal trigeminal nucleus, reticular formation, dorsal motor vagus, and in a few other nuclei.
|
| TS22: cerebral cortex intermediate zone |
Trace |
|
|
|
| TS22: cortical subplate |
Trace |
|
|
|
| TS22: cerebral aqueduct |
Trace |
Regionally restricted |
|
Expression is in the periaqueductal gray area.
|
| TS22: midbrain |
Weak |
Non-Uniform |
|
Expression is in the dorsal raphe, superior and inferior colliculus, and is very weak in the substantia nigra.
|
| TS22: thalamus |
Weak |
Non-Uniform |
|
Expression is weak in the medial thalamus and is very weak in the dorsal, ventral, lateral thalamus, and reticular nuclei, and is absent in the lateral geniculate nuclei.
|
| TS22: cerebral cortex marginal layer |
Absent |
|
|
|
| TS22: epithalamus |
Absent |
|
|
|
Specimen
Table 1 E16:
embryonic day 16.5
(more )
Specimen
Table 1 E16:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 16.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: main olfactory bulb |
Very strong |
Non-Uniform |
|
Expression is in the mitral layer, is strong in the olfactory ventricle and is weak in the glomerular layer.
|
| TS24: diencephalon |
Very strong |
Regionally restricted |
|
Expression is in the subcomissural organ.
|
| TS24: cortical plate |
Strong |
|
|
|
| TS24: piriform cortex |
Strong |
|
|
|
| TS24: superior colliculus |
Strong |
|
|
|
| TS24: hippocampus |
Strong |
Non-Uniform |
|
Expression is moderate in the dentate gyrus and is very weak in the fimbria/fornix.
|
| TS24: thalamus |
Strong |
Non-Uniform |
|
Expression is in the lateral geniculate and reticulate nuclei, moderate in lateral and ventral thalamus, weak in medial and dorsal thalamus.
|
| TS24: hypothalamus |
Strong |
Regionally restricted |
|
Expression is in paraventricular nuclei and arcuate nuclei, moderate in dorsal nuclei, and weak in ventral nuclei.
|
| TS24: cerebral aqueduct |
Very strong |
Regionally restricted |
|
Expression is in the periaqueductal gray area.
|
| TS24: cerebellum |
Strong |
Regionally restricted |
|
Expression is in the upper rhombic lip and Purkinje layer, moderate in the deep nuclei and the external granular layer.
|
| TS24: brainstem |
Strong |
Regionally restricted |
|
Expression is in the floor plate and in numerous nuclei. Absent in inferior olive.
|
| TS24: telencephalon |
Moderate |
Regionally restricted |
|
Expression is in the cingulate and retrospinal cortex, and entorhinal cortex.
|
| TS24: rostral migratory stream |
Moderate |
Regionally restricted |
|
Expression in subventricular zone/rostral migratory stream.
|
| TS24: telencephalon subventricular zone |
Moderate |
Regionally restricted |
|
Expression in subventricular zone/rostral migratory stream.
|
| TS24: caudate-putamen |
Moderate |
|
|
|
| TS24: cortical subplate |
Moderate |
|
|
|
| TS24: epithalamus |
Moderate |
|
|
|
| TS24: basal ganglia |
Moderate |
Regionally restricted |
|
Expression is moderate in the globus pallidus, amygdaloid complex, andaccumbens nucleus, and dorso-lateral septum, weak in medial septum and taenia tecta.
|
| TS24: forebrain |
Moderate |
Regionally restricted |
|
Expression is moderate in the globus pallidus, amygdaloid complex, andaccumbens nucleus, and dorso-lateral septum, weak in medial septum and taenia tecta.
|
| TS24: midbrain |
Moderate |
Regionally restricted |
|
Expression is in dorsal raphe and is weak in substantia nigra.
|
| TS24: cerebral cortex ventricular layer |
Weak |
|
|
|
| TS24: inferior colliculus |
Weak |
|
|
|
| TS24: cerebral cortex intermediate zone |
Trace |
|
|
|
| TS24: ganglionic eminence |
Trace |
|
|
|
| TS24: cerebral cortex marginal layer |
Absent |
|
|
|
Specimen
Table 1 E18:
embryonic day 18.5
(more )
Specimen
Table 1 E18:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
embryonic day 18.5
|
|
Age Note:
|
Age normalized so that noon of plug day = E0.5.
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: main olfactory bulb |
Very strong |
Regionally restricted |
|
Expression is in the mitral cell layer, strong in the granular layer, and is weak in the glomerular layer.
|
| TS26: caudate-putamen |
Strong |
|
|
|
| TS26: cortical plate |
Strong |
|
|
|
| TS26: dentate gyrus |
Strong |
|
|
|
| TS26: hippocampus CA1 |
Strong |
|
|
|
| TS26: hippocampus CA2 |
Strong |
|
|
|
| TS26: periaqueductal grey |
Strong |
|
|
|
| TS26: piriform cortex |
Strong |
|
|
|
| TS26: superior colliculus |
Strong |
|
|
|
| TS26: telencephalon |
Strong |
Regionally restricted |
|
Expression is in the cingulate and retrospinal cortex, and entorhinal cortex.
|
| TS26: rostral migratory stream |
Strong |
Regionally restricted |
|
Expression in subventricular zone/rostral migratory stream.
|
| TS26: telencephalon subventricular zone |
Strong |
Regionally restricted |
|
Expression in subventricular zone/rostral migratory stream.
|
| TS26: midbrain |
Strong |
Regionally restricted |
|
Expression is in dorsal raphe and is weak in substantia nigra.
|
| TS26: hippocampus |
Strong |
Regionally restricted |
|
Expression is in the subiculum, very weak in the fimbria/fornix, and absent in alveus.
|
| TS26: forebrain |
Strong |
Regionally restricted |
|
Expression is in the dorso-lateral septum, taenia tecta, and amygdaloid complex, moderate in globus pallidus, and accumbens nucleus, weak in medial septum.
|
| TS26: diencephalon |
Strong |
Regionally restricted |
|
Expression is in the subcomissural organ.
|
| TS26: thalamus |
Strong |
Non-Uniform |
|
Expression is in the lateral geniculate, reticulate nuclei, and ventral thalamus, moderate in lateral, medial and dorsal thalamus.
|
| TS26: hypothalamus |
Strong |
Regionally restricted |
|
Expression is in paraventricular nuclei and arcuate nuclei, moderate in dorsal nuclei, and weak in ventral nuclei.
|
| TS26: cortical subplate |
Moderate |
|
|
|
| TS26: epithalamus |
Moderate |
|
|
|
| TS26: hippocampus CA3 |
Moderate |
|
|
|
| TS26: cerebellum |
Strong |
Regionally restricted |
|
Expression is strong in the Purkinje layer and moderate in the upper rhombic lip, the deep nuclei and the external granular layer.
|
| TS26: brainstem |
Strong |
Regionally restricted |
|
Expression is in the floor plate and in numerous nuclei.
|
| TS26: brainstem nucleus |
Strong |
Regionally restricted |
|
Expression is in the floor plate and in numerous nuclei.
|
| TS26: cerebral cortex ventricular zone |
Weak |
|
|
|
| TS26: inferior colliculus |
Weak |
|
|
|
| TS26: cerebral cortex intermediate zone |
Trace |
|
|
|
| TS26: cerebral cortex marginal zone |
Absent |
|
|
|
Specimen
Table 1 P0:
postnatal day 0
(more )
Specimen
Table 1 P0:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 0
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P5:
postnatal day 5
(more )
Specimen
Table 1 P5:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P10:
postnatal day 10
(more )
Specimen
Table 1 P10:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 10
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P15:
postnatal day 15
(more )
Specimen
Table 1 P15:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 15
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 P21:
postnatal day 21
(more )
Specimen
Table 1 P21:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal day 21
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
Specimen
Table 1 A:
postnatal adult
(more )
Specimen
Table 1 A:
(close )
|
Genetic Background:
|
OF1
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Analysis Tools