Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wnt2tm1.1(rtTA)Eem
Name:	wingless-type MMTV integration site family, member 2; targeted mutation 1.1, Edward E Morrisey
MGI ID:	MGI:4361155
Synonyms:	Wnt2-
Gene:	Wnt2  Location: Chr6:17988939-18030584 bp, - strand  Genetic Position: Chr6, 8.08 cM, cytoband A2-A3.1
Alliance:	Wnt2tm1.1(rtTA)Eem page

Germline Transmission:	Earliest citation of germline transmission: J:153098
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Transactivator) Mutations:    Insertion, Intragenic deletion   Mutation details: The coding region in exon 1 was replaced with a reverse tet-activator (rtTA). A downstream FRT flanked neo cassette was removed by germ line, flp mediated recombination. (J:153098)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt2 Mutation:	26 strains or lines available

Original:	J:153098 Goss AM, et al., Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev Cell. 2009 Aug;17(2):290-8
All:	2 reference(s)