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Fabp7tm2(cre/PGR*)Ksak
Targeted Allele Detail
Summary
Symbol: Fabp7tm2(cre/PGR*)Ksak
Name: fatty acid binding protein 7, brain; targeted mutation 2, Kenji Sakimura
MGI ID: MGI:4360725
Synonyms: BFABP-CrePR, Fabp7tm1(crePR)Ksak, Fabp7tm2(cre/PGR)Ksak
Gene: Fabp7  Location: Chr10:57661019-57664546 bp, + strand  Genetic Position: Chr10, 29.25 cM
Alliance: Fabp7tm2(cre/PGR*)Ksak page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:104881
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    mifepristone
Mutation:    Insertion
 
Fabp7tm2(cre/PGR*)Ksak expression driven by 1 gene
 
Mutation detailsThe endogenous gene's promoter drives expression of a DNA sequence encoding a fusion protein in which Cre recombinase is joined to the ligand binding domain (LBD) of the human progesterone receptor lacking the carboxyl terminal 42 amino acids. The chimeric recombinase protein is not constitutively active; its activity is inducible by binding of the synthetic progesterone analog RU486 to the truncated progesterone LBD. (J:104881, J:122587)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Fabp7 (mouse)
Summary of all recombinase alleles driven by Fabp7.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fabp7 Mutation:  16 strains or lines available
References
Original:  J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory