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Gene Expression Data
Assay Details
Assay
Reference: J:16739 Huynh DP, et al., Differential expression and tissue distribution of type I and type II neurofibromins during mouse fetal development. Dev Biol. 1994 Feb;161(2):538-51
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4360536
Gene symbol: Nf1
Gene name: neurofibromin 1
Antibody: NF1C antibody
Detection system: Secondary antibody
Results
Specimen 2 E8: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: embryo Weak 2_E8
Specimen 2 E10: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: 1st branchial arch Present 2_E10
TS16: heart atrium Present 2_E10
TS16: nervous system Present 2_E10
TS16: primitive ventricle Present 2_E10
Specimen 2 E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: nervous system Strong Non-Uniform 2_E11
TS18: neural tube mantle layer Strong 2_E11
TS18: neural tube ventricular layer Strong 2_E11
TS18: dorsal root ganglion Present 2_E11
TS18: heart Present 2_E11
TS18: liver Present 2_E11
TS18: lung Present 2_E11
TS18: stomach Present 2_E11
Specimen 2 E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Strong 2_E12
TS20: heart Strong 2_E12
TS20: liver Strong 2_E12
TS20: mesonephric tubule Strong 2_E12
TS20: metanephros Strong 2_E12
TS20: stomach epithelium Strong 2_E12
TS20: bronchus Strong Regionally restricted 2_E12 Expression is in the bronchial tubules.
Specimen 2 E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: dermis Very strong 2_E13 Expression is intense in all embryonic tissues including the dermis and epidermis.
TS21: embryo Very strong 2_E13 Expression is intense in all embryonic tissues including the dermis and epidermis.
TS21: epidermis Very strong 2_E13 Expression is intense in all embryonic tissues including the dermis and epidermis.
Specimen 2 E16: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: embryo Strong Non-Uniform 2_E16 The authors state that some of the dark staining in some tissues is related to high cell density.
TS24: nervous system Strong 2_E16
TS24: oral epithelium Strong Regionally restricted 2_E16 Expression is in the buccal epithelium.
Specimen Not shown: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: embryo Weak
Specimen 3A E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: neural tube mantle layer Strong Regionally restricted 3A E11 Expression is in postmitotic neuroepithelia.
TS18: neural tube ventricular layer Present Regionally restricted 3A E11 Expression is less strong in undifferentiated dividing neuroepithelia.
TS18: neural tube marginal layer Absent 3A E11
Specimen 3A E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: spinal cord mantle layer Strong 3A E12
Specimen 3A E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: spinal cord mantle layer Strong 3A E13
Specimen 3A E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: spinal cord mantle layer Strong 3A E14
Specimen 3B E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: dorsal root ganglion Present 3B E11
Specimen 3B E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Strong 3B E12
Specimen 3B E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: dorsal root ganglion Weak 3B E13
Specimen 3B E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: dorsal root ganglion Weak 3B E14
Specimen 3C E11: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: heart Weak 3C E11
Specimen 3C E12: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: heart Strong 3C E12
Specimen 3C E13: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: heart Weak 3C E13
Specimen 3C E14: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: heart Weak 3C E14
TS22: liver Present 3C E14
Specimen 4B: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: cortical plate Present 4B
TS23: cerebral cortex intermediate zone Present Single cells 4B
TS23: cerebral cortex ventricular layer Trace Single cells 4B Barely visible staining.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory