Gene Expression Data
Assay Details
Assay
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Reference:
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J:36890
Saga Y, et al., Mice develop normally without tenascin. Genes Dev. 1992 Oct;6(10):1821-31
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:4359755
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Gene symbol:
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Tnc
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Gene name:
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tenascin C
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Reporter:
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lacZ
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Direct Detection
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Assay notes:
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The specimens were fixed in 2% paraformaldehyde-0.2% glutaraldehyde.
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Results
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Specimen
2A:
embryonic day 10.0; Tnctm1Sia/Tnc +
(more )
Note: This is a lateral view.
Specimen
2A:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6 * CBA
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Mutant Allele(s):
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Tnctm1Sia/Tnc+
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Age:
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embryonic day 10.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Other - See Notes
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Note:
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This is a lateral view.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: embryo |
Present |
|
2A
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Previous studies have shown that expression in the pericardium precedes later expression in the somites and cartilage.
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Specimen
2B:
embryonic day 11.0; Tnctm1Sia/Tnc +
(more )
Note: This is a lateral view.
Specimen
2B:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6 * CBA
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Mutant Allele(s):
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Tnctm1Sia/Tnc+
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Age:
|
embryonic day 11.0
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
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Not Specified
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Type:
|
whole mount
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Fixation:
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Other - See Notes
|
Note:
|
This is a lateral view.
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: embryo |
Present |
|
2B
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Previous studies have shown that expression in the pericardium precedes later expression in the somites and cartilage.
|
Specimen
2C:
embryonic day 12.0; Tnctm1Sia/Tnc +
(more )
Note: This is a lateral view.
Specimen
2C:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6 * CBA
|
Mutant Allele(s):
|
Tnctm1Sia/Tnc+
|
Age:
|
embryonic day 12.0
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Age Note:
|
Age of embryo at noon of plug day not specified in reference.
|
Sex:
|
Not Specified
|
Type:
|
whole mount
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Fixation:
|
Other - See Notes
|
Note:
|
This is a lateral view.
|
Structure |
Level |
Pattern |
Image |
Note |
TS20: embryo |
Present |
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2C
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Previous studies have shown that expression in the pericardium precedes later expression in the somites and cartilage.
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Specimen
2E:
postnatal day 2; Tnctm1Sia/Tnc +
(more )
Note: This is a sagittal section.
Specimen
2E:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6 * CBA
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Mutant Allele(s):
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Tnctm1Sia/Tnc+
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Age:
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postnatal day 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Note:
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This is a sagittal section.
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Structure |
Level |
Pattern |
Image |
Note |
TS27: lung alveolus |
Present |
Regionally restricted |
2E
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Expression is present in relatively large cells located on the alveolar walls adjacent to type-I alveolar cells and at the apex of protrusion of the alveolar septa.
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Specimen
2G:
embryonic day 18.0; Tnctm1Sia/Tnc +
(more )
Specimen
2G:
(close )
Genetic Background:
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involves: BALB/c * C57BL/6 * CBA
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Mutant Allele(s):
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Tnctm1Sia/Tnc+
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Age:
|
embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS26: cerebellum |
Present |
Regionally restricted |
2G
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Expression is present in the Bergmann glial cells in the developing Purkinje cell layer.
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Specimen
4 lung +/-:
postnatal day 12; Tnctm1Sia/Tnc +
(more )
Specimen
4 lung +/-:
(close )
Genetic Background:
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involves: BALB/c * C57BL/6 * CBA
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Mutant Allele(s):
|
Tnctm1Sia/Tnc+
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Age:
|
postnatal day 12
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Sex:
|
Not Specified
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Type:
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section
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Fixation:
|
Other - See Notes
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Embedding:
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Cryosection
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Specimen
4 lung -/-:
(close )
Genetic Background:
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involves: BALB/c * C57BL/6 * CBA
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Mutant Allele(s):
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Tnctm1Sia/Tnctm1Sia
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Age:
|
postnatal day 12
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lung |
Present |
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4A lung -/- LacZ
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As expected, expression levels are stronger in homozygotes compared to heterozygotes.
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Specimen
4 thymus +/-:
postnatal day 12; Tnctm1Sia/Tnc +
(more )
Specimen
4 thymus +/-:
(close )
Genetic Background:
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involves: BALB/c * C57BL/6 * CBA
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Mutant Allele(s):
|
Tnctm1Sia/Tnc+
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Age:
|
postnatal day 12
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Sex:
|
Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
4 thymus -/-:
(close )
Genetic Background:
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involves: BALB/c * C57BL/6 * CBA
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Mutant Allele(s):
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Tnctm1Sia/Tnctm1Sia
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Age:
|
postnatal day 12
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Sex:
|
Not Specified
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Type:
|
section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: thymus |
Present |
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4A thymus -/- LacZ
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As expected, expression levels are stronger in homozygotes compared to heterozygotes.
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Specimen
4 cerebellum +/-:
postnatal day 12; Tnctm1Sia/Tnc +
(more )
Specimen
4 cerebellum +/-:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6 * CBA
|
Mutant Allele(s):
|
Tnctm1Sia/Tnc+
|
Age:
|
postnatal day 12
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Sex:
|
Not Specified
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Type:
|
section
|
Fixation:
|
Other - See Notes
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Embedding:
|
Cryosection
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Specimen
4 cerebellum -/-:
(close )
Genetic Background:
|
involves: BALB/c * C57BL/6 * CBA
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Mutant Allele(s):
|
Tnctm1Sia/Tnctm1Sia
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Age:
|
postnatal day 12
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
Other - See Notes
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Embedding:
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Cryosection
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