About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:15850 Guillemot F, et al., Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell. 1993 Nov 5;75(3):463-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4359442
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to alkaline phosphatase
Results
Specimen 4C: embryonic day 12.5 (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS20: sympathetic ganglion Present 4C

Specimen 4D: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS20: sympathetic ganglion Absent 4D

Specimen wild type: embryonic day 12.5 (more )
Note: This section is from the posterior thoracic region.
Structure Level Pattern Image Note
TS20: sympathetic ganglion Present

Specimen mutant: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This section is from the posterior thoracic region.
Structure Level Pattern Image Note
TS20: sympathetic ganglion Present Single cells This section is from the posterior thoracic region.

Specimen wild type: embryonic day 14.5 (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS22: sympathetic ganglion Present

Specimen mutant: embryonic day 14.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS22: sympathetic ganglion Absent

Specimen wild type: embryonic day 17.5 (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS25: sympathetic ganglion Present

Specimen mutant: embryonic day 17.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS25: sympathetic ganglion Absent

Specimen 5C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Present Regionally restricted 5C Expression is present in the condensing sympathetic ganglia.

Specimen 5E: embryonic day 10.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Absent 5E There is no expression present in the condensing sympathetic ganglia.

Specimen 6G: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: adrenal medulla Present 6G Expression is present in the chromaffin cells.

Specimen 6H: embryonic day 17.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS25: adrenal medulla Present 6H Expression is present in the chromaffin cells. There are fewer expressing cells in the mutant compared to the wild type.

Specimen wild type: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS22: adrenal medulla Present Expression is present in chromaffin cells.

Specimen mutant: embryonic day 13.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS22: adrenal medulla Present Expression is present in the chromaffin cells. There are fewer expressing cells in the mutant compared to the wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/06/2026
MGI 6.24
The Jackson Laboratory