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Gene Expression Data
Assay Details
Assay
Reference: J:15850 Guillemot F, et al., Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell. 1993 Nov 5;75(3):463-76
Assay type: RNA in situ
MGI Accession ID: MGI:4359441
Gene symbol: Stmn2
Gene name: stathmin-like 2
Probe: SCG10-8
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen wild type: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: brain Present Expression is present in the neurons.
TS27: olfactory epithelium Present Regionally restricted Expression is present in the neurons but not the basal and sustentacular cells.

Specimen mutant: postnatal newborn; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS27: brain Present Expression is present in the neurons. Expression is the same in mutants as in wild type.
TS27: olfactory epithelium Present Regionally restricted The olfactory epithelium is essentially devoid of expression, with the exception of a few areas where scattered expressing cells could be observed.

Specimen wild type: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Expression is present in the neurons.

Specimen mutant: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS20: spinal cord Present Expression is present in the neurons. Expression is the same in mutants as in wild type.

Specimen 4A: embryonic day 12.5 (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS20: sympathetic ganglion Present 4A
TS20: dorsal root ganglion Present 4A

Specimen 4B: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS20: sympathetic ganglion Absent 4B
TS20: dorsal root ganglion Present 4B Expression in the mutant is the same as in wild type.

Specimen 4E: embryonic day 12.5 (more )
Note: This section is from the posterior thoracic region.
Structure Level Pattern Image Note
TS20: sympathetic ganglion Present 4E

Specimen 4F: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This section is from the posterior thoracic region.
Structure Level Pattern Image Note
TS20: sympathetic ganglion Present Single cells 4F Expression is present in occasional cells.

Specimen wild type: embryonic day 14.5 (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS22: sympathetic ganglion Present

Specimen mutant: embryonic day 14.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS22: sympathetic ganglion Absent

Specimen wild type: embryonic day 17.5 (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS25: sympathetic ganglion Present

Specimen mutant: embryonic day 17.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This section is from the anterior thoracic region.
Structure Level Pattern Image Note
TS25: sympathetic ganglion Absent

Specimen 4G: embryonic day 17.5 (more )
Note: This section is from the cardiac region.
Structure Level Pattern Image Note
TS25: parasympathetic nervous system Present Regionally restricted 4G Expression is present in the parasympathetic ganglion.
TS25: enteric nervous system Present Regionally restricted 4G Expression is present in the enteric neurons of the foregut, located in the wall of the esophagus.

Specimen 4H: embryonic day 17.5; Ascl1tm1And/Ascl1tm1And (more )
Note: This section is from the cardiac region.
Structure Level Pattern Image Note
TS25: parasympathetic nervous system Absent 4H There is no expression in the parasympathetic ganglion.
TS25: enteric nervous system Absent 4H There is no expression present in the enteric neurons of the foregut, located in the wall of the esophagus.

Specimen wild type: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Present Regionally restricted Expression is present in the condensing sympathetic ganglia.

Specimen mutant: embryonic day 10.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS17: sympathetic nervous system Absent There is no expression in the condensing sympathetic ganglia.

Specimen 6E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sympathetic ganglion Present 6E

Specimen 6F: embryonic day 12.5; Ascl1tm1And/Ascl1tm1And (more )
Structure Level Pattern Image Note
TS20: sympathetic ganglion Absent 6F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory