Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kdm1btm1.1Tche
Name:	lysine (K)-specific demethylase 1B; targeted mutation 1.1, Taiping Chen
MGI ID:	MGI:4359289
Synonyms:	Aof11loxP
Gene:	Kdm1b  Location: Chr13:47196849-47238085 bp, + strand  Genetic Position: Chr13, 24.5 cM
Alliance:	Kdm1btm1.1Tche page

Germline Transmission:	Earliest citation of germline transmission: J:152382
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A floxed beta-Geo cassette was inserted in intron 16 and an additional loxP site was inserted in intron 13. Exons 14-16 are thus flanked by loxP sites. Mice were crossed with transgenic mice carrying an unspecified Zp3-cre transgene to excise exons 14-16 and the beta Geo cassette. (J:152382)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kdm1b Mutation:	63 strains or lines available

Original:	J:152382 Ciccone DN, et al., KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature. 2009 Sep 17;461(7262):415-8
All:	2 reference(s)