Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(TXNRD2,COMT,ARVCF)1Nhir
Name:	transgene insertion 1, Noboru Hiroi
MGI ID:	MGI:4358257
Transgene:	Tg(TXNRD2,COMT,ARVCF)1Nhir  Location: unknown
Alliance:	Tg(TXNRD2,COMT,ARVCF)1Nhir page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(TXNRD2,COMT,ARVCF)1Nhir expresses 3 genes Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human ARVCF (421) Arvcf  (MGI:109620) human COMT (1312) Comt  (MGI:88470) human TXNRD2 (10587) Txnrd2  (MGI:1347023)   Mutation details: The transgenic construct consists of a bacterial artificial chromosome (BAC) clone 467.8 encoding a 190 kb segment from human 22q11.2 including TXNRD2, COMT, and ARVCF. Transgenic mice were generated by microinjection into FVB mouse embryos. Mice have one to two copies of the transgene. (J:152368)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:152368 Suzuki G, et al., Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice. Hum Mol Genet. 2009 Oct 15;18(20):3914-25
All:	1 reference(s)