Tg(Mef2c-ALPP)1Blk
Transgene Detail
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| Symbol: |
Tg(Mef2c-ALPP)1Blk |
| Name: |
transgene insertion 1, Brian L Black |
| MGI ID: |
MGI:4356434 |
| Transgene: |
Tg(Mef2c-ALPP)1Blk Location: unknown
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| Alliance: |
Tg(Mef2c-ALPP)1Blk page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: A 3970-bp segment located from 16.3-20.3 kb downstream of Mef2c exon 1 and 51.1-55.1 kb upstream of the first coding exon (exon 5) was used to direct human placental alkaline phosphatase expression. This region of the mouse Mef2c gene contains enhancer and promoter sequences sufficient to direct expression in mouse embryos to the anterior heart field and its derivatives in the pharyngeal mesoderm, the right ventricle, and the outflow tract. (details provided by Dr. Brian L Black, personal Communication)
(J:98489, J:152141)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:98489 Stennard FA, et al., Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development. 2005 May;132(10):2451-62 |
| All: |
2 reference(s) |
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