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Tg(Gata4*G2-lacZ)1Blk
Transgene Detail
Summary
Symbol: Tg(Gata4*G2-lacZ)1Blk
Name: transgene insertion 1, Brian L Black
MGI ID: MGI:4356300
Transgene: Tg(Gata4*G2-lacZ)1Blk  Location: unknown  
Alliance: Tg(Gata4*G2-lacZ)1Blk page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA 4368 bp fragment containin the highly conserved G2 segment located between 45.3 and 40.9 kb upstream of the Gata4 gene contains the Gata4 lateral mesoderm enhancer. This sequence has the GenBank Accession #AY763588. It was used to direct expression of lacZ in conjunction with the Hspa1b minimal promoter. (J:100426)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:100426 Rojas A, et al., Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element. Development. 2005 Aug;132(15):3405-17
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory