Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Prickle1tm1Nue
Name:	prickle planar cell polarity protein 1; targeted mutation 1, Naoto Ueno
MGI ID:	MGI:4356107
Synonyms:	Prickle1LacZ
Gene:	Prickle1  Location: Chr15:93396995-93493772 bp, - strand  Genetic Position: Chr15, 47.69 cM
Alliance:	Prickle1tm1Nue page

Germline Transmission:	Earliest citation of germline transmission: J:151993
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Part of exon 2 was replaced with a lacZ-neo cassette via homologous recombination. Immunofluorescent analysis of homozygous embryos confirmed the absence of protein expression. (J:151993)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prickle1 Mutation:	34 strains or lines available

Original:	J:151993 Tao H, et al., Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14426-31
All:	5 reference(s)