Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Prrx1-cre/ERT2,-EGFP)1Smkm
Name:	transgene insertion 1, Shunichi Murakami
MGI ID:	MGI:4355342
Synonyms:	Prx1CreER-GFP
Transgene:	Tg(Prrx1-cre/ERT2,-EGFP)1Smkm  Location: unknown
Alliance:	Tg(Prrx1-cre/ERT2,-EGFP)1Smkm page

Strain of Origin:

(C57BL/6 x SJL)F2

Transgene Type:    Transgenic (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Tg(Prrx1-cre/ERT2,-EGFP)1Smkm expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Prrx1   Mutation details: The cre/ERT2 cDNA was cloned downstream of a 2.4 kb Prrx1 promoter. cDNA encoding an IRES-EGFP was inserted downstream of the cre/ERT2 sequence. This construct was injected into fertilized oocytes and 3 founders that expressed the transgene in the limbs were identified. Crosses to Rosa26-lacZ reporter mice identified two lines which had intense X-gal staining upon induction with tamoxifen. One line was chosen for further analysis. (J:151681)

Activity:	Tissue activity of this recombinase allele
Driver:	Prrx1 (species not specified) Summary of all recombinase alleles driven by Prrx1. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:151681 Kawanami A, et al., Mice expressing GFP and CreER in osteochondro progenitor cells in the periosteum. Biochem Biophys Res Commun. 2009 Aug 28;386(3):477-82
All:	26 reference(s)