Tg(Col1a1-BMP3)1Vrs
Transgene Detail
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| Symbol: |
Tg(Col1a1-BMP3)1Vrs |
| Name: |
transgene insertion 1, Vicki Rosen |
| MGI ID: |
MGI:4354301 |
| Transgene: |
Tg(Col1a1-BMP3)1Vrs Location: unknown
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| Alliance: |
Tg(Col1a1-BMP3)1Vrs page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Col1a1-BMP3)1Vrs expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
BMP3 (651) |
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Mutation details: A human BMP3 gene is driven by the 3.2-kb fragment of the mouse alpha (1) I collagen promoter. BMP3 is expressed in the perichondrium, periosteum, osteoprogenitors, osteoblasts, odontoblasts, and tendon starting at E14.5. Two lines of mice were created.
(J:151466)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:151466 Gamer LW, et al., Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures. Dev Dyn. 2009 Aug 3;238(9):2374-2381 |
| All: |
1 reference(s) |
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