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Tg(Col1a1-BMP3)1Vrs
Transgene Detail
Summary
Symbol: Tg(Col1a1-BMP3)1Vrs
Name: transgene insertion 1, Vicki Rosen
MGI ID: MGI:4354301
Transgene: Tg(Col1a1-BMP3)1Vrs  Location: unknown  
Alliance: Tg(Col1a1-BMP3)1Vrs page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Col1a1-BMP3)1Vrs expresses 1 gene
 
Mutation detailsA human BMP3 gene is driven by the 3.2-kb fragment of the mouse alpha (1) I collagen promoter. BMP3 is expressed in the perichondrium, periosteum, osteoprogenitors, osteoblasts, odontoblasts, and tendon starting at E14.5. Two lines of mice were created. (J:151466)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:151466 Gamer LW, et al., Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures. Dev Dyn. 2009 Aug 3;238(9):2374-2381
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory