Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mir96Dmdo
Name:	microRNA 96; diminuendo
MGI ID:	MGI:4354110
Synonyms:	DEA12, diminuendo, Dmdo
Gene:	Mir96  Location: Chr6:30169445-30169550 bp, - strand  Genetic Position: Chr6, 12.52 cM
Alliance:	Mir96Dmdo page

Strain of Origin:

C3HeB/FeJ

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU induces an A to T transversion in the seed region resulting in transcript destabilization and translational inhibition. An additional mutation (C to T) was identified in exon 5 of Akr1b10. However, it does not alter the codon and is not thought to cause the phenotype associated with this mutant. (J:151354) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

3 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mir96 Mutation:	6 strains or lines available

Original:	J:151354 Lewis MA, et al., An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice. Nat Genet. 2009 May;41(5):614-8
All:	6 reference(s)