Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cacna2d1tm1Aschw
Name:	calcium channel, voltage-dependent, alpha2/delta subunit 1; targeted mutation 1, Arnold Schwartz
MGI ID:	MGI:4353680
Synonyms:	alpha-2/delta-1-, alpha2/delta-1-
Gene:	Cacna2d1  Location: Chr5:16139786-16579502 bp, + strand  Genetic Position: Chr5, 6.56 cM
Alliance:	Cacna2d1tm1Aschw page

Germline Transmission:	Earliest citation of germline transmission: J:151101
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Exon 2 was disrupted by insertion of a neomycin cassette. Gene inactivation was confirmed by no signal in immunoblot analysis of homozygote heart, brain and skeletal muscle extracts. (J:151101)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cacna2d1 Mutation:	78 strains or lines available

Original:	J:151101 Fuller-Bicer GA, et al., Targeted disruption of the voltage-dependent calcium channel alpha2/delta-1-subunit. Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H117-24
All:	12 reference(s)