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AspmGt(AA0137)Wtsi
Gene trapped Allele Detail
Summary
Symbol: AspmGt(AA0137)Wtsi
Name: abnormal spindle microtubule assembly; gene trap AA0137, Wellcome Trust Sanger Institute
MGI ID: MGI:4345319
Synonyms: Aspm1-7
Gene: Aspm  Location: Chr1:139382510-139421829 bp, + strand  Genetic Position: Chr1, 61.45 cM, cytoband F
Alliance: AspmGt(AA0137)Wtsi page
Mutation
origin
Mutant Cell Line:  AA0137
Germline Transmission:  Earliest citation of germline transmission: J:164424
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0lxr
 
Mutation detailsThe gene trap vector was determined to have integrated between exons 7 and 8 such that the protein product contains only the microtubule binding domain. (J:164424)
Sequence Tags: 
Sequence tag details (1 tag)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aspm Mutation:  138 strains or lines available
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory