Akr1a1Gt(OST222400)Lex
Gene trapped Allele Detail
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| Symbol: |
Akr1a1Gt(OST222400)Lex |
| Name: |
aldo-keto reductase family 1, member A1; gene trap OST222400, Lexicon Genetics |
| MGI ID: |
MGI:4239556 |
| Synonyms: |
GR- |
| Gene: |
Akr1a1 Location: Chr4:116493707-116508871 bp, - strand Genetic Position: Chr4, 53.26 cM, cytoband C7
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| Alliance: |
Akr1a1Gt(OST222400)Lex page
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Severe loss of bone and fractures in the long bones of Akr1a1Gt(OST222400)Lex/Akr1a1Gt(OST222400)Lex mice
Show the 5 phenotype image(s) involving this allele.
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| Mutant Cell Line: |
OST222400 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:164548
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| Parent Cell Line: |
Lex-1 (ES Cell)
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| Strain of Origin: |
129S5/SvEvBrd
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| Project Collection: |
Lexicon
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| Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
| Mutation: |
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Insertion of gene trap vector
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Mutation details: The gene trap vector inserted upstream of the exon containing the start codon. Protein assay confirmed the absence of glucoronate reducing activity.
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| Sequence Tags: |
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Sequence tag details (1 tag)
| Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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| Genome Context: |
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Genome Browser view of this mutation
86 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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Schema for generation of the Akr1a1Gt(OST222400)Lex allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Akr1a1 Mutation: |
30 strains or lines available
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| Original: |
J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008; |
| All: |
3 reference(s) |
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Analysis Tools
