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Atad5Gt(RRF055)Byg
Gene trapped Allele Detail
Summary
Symbol: Atad5Gt(RRF055)Byg
Name: ATPase family, AAA domain containing 5; gene trap RRF055, BayGenomics
MGI ID: MGI:4127920
Synonyms: Atad5m
Gene: Atad5  Location: Chr11:79980226-80026620 bp, + strand  Genetic Position: Chr11, 47.48 cM
Alliance: Atad5Gt(RRF055)Byg page
Atad5Gt(RRF055)Byg/Atad5+ mice are tumor-prone

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Mutant Cell Line:  RRF055
Germline Transmission:  Earliest citation of germline transmission: J:176672
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation detailsThe gene trap inserted into intron 18. A 50% reduction in protein expression was confirmed by western blot analysis on mouse embryonic fibroblasts from heterozygous mice. (J:176672)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Insertional mutagenesis to generate the Atad5Gt(RRF055)Byg allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Atad5Gt(RRF055)Byg
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atad5 Mutation:  100 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory