Et(cre/ERT2)7089Rdav
Transgene Detail
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Symbol: |
Et(cre/ERT2)7089Rdav |
Name: |
enhancer trap 7089, Ron Davis |
MGI ID: |
MGI:3852340 |
Transgene: |
Et(cre/ERT2)7089Rdav Location: unknown
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Alliance: |
Et(cre/ERT2)7089Rdav page
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Strain of Origin: |
C57BL/6J
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Project Collection: |
Neuroscience Blueprint cre
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Et(cre/ERT2)7089Rdav expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Et(cre/ERT2)7089Rdav (MGI:3852238) |
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Mutation details: An enhancer trap transgenic approach was used to generate these mice. The hsyn-bgi-cre:ERT2-bGHpA transgene was designed with the human synapsin minimal promoter (hsyn) minimal promoter driving a cre-ERT2 fusion gene (cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain).A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 7089 was established on a C57BL/6J genetic background.
(J:150856)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Et(cre/ERT2)7089Rdav
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009; |
All: |
2 reference(s) |
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