Et(icre/ERT2)10596Rdav
Transgene Detail
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Symbol: |
Et(icre/ERT2)10596Rdav |
Name: |
enhancer trap 10596, Ron Davis |
MGI ID: |
MGI:3852351 |
Transgene: |
Et(icre/ERT2)10596Rdav Location: unknown
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Alliance: |
Et(icre/ERT2)10596Rdav page
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Strain of Origin: |
C57BL/6J
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Project Collection: |
Neuroscience Blueprint cre
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Et(icre/ERT2)10596Rdav expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Et(icre/ERT2)10596Rdav (MGI:3852320) |
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Mutation details: An enhancer trap transgenic approach was used to generate these mice. The hsyn-bgi-cre:ERT2-bGHpA transgene was designed with the human synapsin minimal promoter (hsyn) minimal promoter driving an icre-ERT2 fusion gene (a codon-improved cre recombinase sequence fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain). A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 10596 was established on a C57BL/6J genetic background.
(J:150856)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Et(icre/ERT2)10596Rdav
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009; |
All: |
3 reference(s) |
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