Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Cd8a-cre)1Itan
Name:	transgene insertion 1, Ichiro Taniuchi
MGI ID:	MGI:3851193
Synonyms:	E8I-Cre, E8ICre.GFP
Transgene:	Tg(Cd8a-cre)1Itan  Location: unknown
Alliance:	Tg(Cd8a-cre)1Itan page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Recombinase, Reporter) Mutation:    Insertion   Tg(Cd8a-cre)1Itan expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Cd8a   Mutation details: The 1.6 kb core of the E8I Cd8 locus enhancer region was inserted in front of the Cd8a promoter, and cre recombinase cDNA and an IRES-GFP-polyA cassette were inserted after the promoter to generated the transgene construct. (J:141009)

Activity:	Tissue activity of this recombinase allele
Driver:	Cd8a (species not specified) Summary of all recombinase alleles driven by Cd8a.

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:141009 Maekawa Y, et al., Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity. Nat Immunol. 2008 Oct;9(10):1140-7
All:	36 reference(s)