Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(HLA-A*1101/H2-Kb)#Sette
Name:	transgene insertion, Alessandro Sette
MGI ID:	MGI:3851009
Synonyms:	HLA-A11, HLA-A11/Kb
Transgene:	Tg(HLA-A*1101/H2-Kb)#Sette  Location: unknown
Alliance:	Tg(HLA-A*1101/H2-Kb)#Sette page

Strain of Origin:

BALB/c or C57BL/6

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Mutation details: The model was created by microinjecting a chimeric transgene combining a fragment of the genomic clone of the human HLA-A*1101 gene that included leader sequence, alpha1 and alpha2 domains ligated to a fragment of the murine H2-Kb gene containing the alpha3, transmembrane and cytoplasmic domains. (J:150565)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:150565 Alexander J, et al., Derivation of HLA-A11/Kb transgenic mice: functional CTL repertoire and recognition of human A11-restricted CTL epitopes. J Immunol. 1997 Nov 15;159(10):4753-61
All:	6 reference(s)