Tg(MMTV-rtTA)4-1Jek
Transgene Detail
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| Symbol: |
Tg(MMTV-rtTA)4-1Jek |
| Name: |
transgene insertion 4-1, Jeffrey E Kudlow |
| MGI ID: |
MGI:3850385 |
| Synonyms: |
MMTV-rtTA, MMTV-rtTA-SV40 |
| Transgene: |
Tg(MMTV-rtTA)4-1Jek Location: unknown
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| Alliance: |
Tg(MMTV-rtTA)4-1Jek page
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| Strain of Origin: |
(C57BL/6 x SJL)
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| Transgene Type: |
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Transgenic (Transactivator) |
| Mutation: |
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Insertion
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Mutation details: The MMTV-rtTA-SV40 transgene was designed with the 1.5 kb mouse mammary tumor virus long terminal repeat (MMTV-LTR) promoter, the reverse tetracycline transactivator gene and VP16 activation domain (rtTA-VP16), and SV40 intron/polyA sequence. The rtTA-VP16-polyA sequence is inserted into exon 3 of the rabbit beta-globin gene immediately following the MMTV promoter. This 3.75 kb transgene was injected into one-cell (C57BL/6 x SJL) mouse zygotes. Mice from founder line 4-1 were bred with C57BL/6;SJL wildtype mice to establish the colony.
(J:134284)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:134284 Whisenhunt TR, et al., Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development. Glycobiology. 2006 Jun;16(6):551-63 |
| All: |
4 reference(s) |
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Analysis Tools
