Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Gh1-rtTA)4-3Jek
Name:	transgene insertion 4-3, Jeffrey E Kudlow
MGI ID:	MGI:3850379
Synonyms:	GH-rtTA
Transgene:	Tg(Gh1-rtTA)4-3Jek  Location: unknown
Alliance:	Tg(Gh1-rtTA)4-3Jek page

Strain of Origin:

(C57BL/6 x SJL)

Transgene Type:    Transgenic (Transactivator) Mutation:    Insertion   Mutation details: The GH-rtTA transgene was designed with a 1.7 kb promoter sequence from the rat growth hormone (Gh1) gene, a reverse tetracycline-regulated transactivator (rtTA) gene, and an SV40 intron/polyA sequence. This 4.5 kb transgene was microinjected into one-cell (C57BL/6 x SJL) mouse zygotes. Mice from founder line 4-3 were bred with C57BL/6;SJL wildtype mice to establish the colony. (J:68692)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:68692 Roh M, et al., Stage-sensitive blockade of pituitary somatomammotrope development by targeted expression of a dominant negative epidermal growth factor receptor in transgenic mice. Mol Endocrinol. 2001 Apr;15(4):600-13
All:	1 reference(s)