Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Prl-tTA)6-5Jek
Name:	transgene insertion 6-5, Jeffrey E Kudlow
MGI ID:	MGI:3850376
Synonyms:	Prl-tTA
Transgene:	Tg(Prl-tTA)6-5Jek  Location: unknown
Alliance:	Tg(Prl-tTA)6-5Jek page

Strain of Origin:

(C57BL/6 x SJL)

Transgene Type:    Transgenic (Transactivator) Mutation:    Insertion   Mutation details: The PRL-tTA transgene was designed with a 3.2 kb promoter sequence from the rat prolactin (Prl) gene, a tetracycline-regulated transactivator (tTA) gene, and an SV40 intron/polyA sequence. This 5.2 kb transgene was microinjected into one-cell (C57BL/6 x SJL) mouse zygotes. Mice from founder line 6-5 were bred with C57BL/6;SJL wildtype mice to establish the colony. (J:68692)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:68692 Roh M, et al., Stage-sensitive blockade of pituitary somatomammotrope development by targeted expression of a dominant negative epidermal growth factor receptor in transgenic mice. Mol Endocrinol. 2001 Apr;15(4):600-13
All:	1 reference(s)