Tg(CAG-RAB9A)500Repa
Transgene Detail
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| Symbol: |
Tg(CAG-RAB9A)500Repa |
| Name: |
transgene insertion 500, Richard E Pagano |
| MGI ID: |
MGI:3849445 |
| Synonyms: |
Rab9TG, Rab9TG |
| Transgene: |
Tg(CAG-RAB9A)500Repa Location: unknown
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| Alliance: |
Tg(CAG-RAB9A)500Repa page
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CAG-RAB9A)500Repa expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
RAB9A (9367) |
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Mutation details: A transgenic construct containing a HA-tagged human RAB9A, member RAS oncogene family, gene (RAB9A) under the control of the CAG promoter (CAGGS, chicken beta actin promoter/enhancer coupled with the cytomegalovirus immediate-early enhancer), was injected into fertilized (C57BL/6 X CBA)F1 X C57BL/6 mouse eggs. Founder line 500 was subsequently established. Expression is approximately 30-fold higher than endogenous Rab9 protein in the liver.
(J:144240)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:144240 Kaptzan T, et al., Development of a Rab9 transgenic mouse and its ability to increase the lifespan of a murine model of Niemann-Pick type C disease. Am J Pathol. 2009 Jan;174(1):14-20 |
| All: |
1 reference(s) |
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Analysis Tools
