B4galt2tm1Masn
Targeted Allele Detail
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Symbol: |
B4galt2tm1Masn |
Name: |
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2; targeted mutation 1, Masahide Asano |
MGI ID: |
MGI:3849305 |
Synonyms: |
beta4GalT-II- |
Gene: |
B4galt2 Location: Chr4:117730197-117740759 bp, - strand Genetic Position: Chr4, 53.7 cM, cytoband D1
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Alliance: |
B4galt2tm1Masn page
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Reduced cortex and enlargement of the lateral ventricle in B4galt2tm1Masn/B4galt2tm1Masn mice
Show the 2 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:149762
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 1 and 2 and part of exon 3 were replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot and RT-PCR analysis on brain extracts.
(J:149762)
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Generation of the B4galt2tm1Masn allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any B4galt2 Mutation: |
11 strains or lines available
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Original: |
J:149762 Yoshihara T, et al., Learning/memory impairment and reduced expression of the HNK-1 carbohydrate in beta4-galactosyltransferase-II-deficient mice. J Biol Chem. 2009 May 1;284(18):12550-61 |
All: |
1 reference(s) |
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