Gene Expression Data
Assay Details
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Assay
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Reference:
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J:147173
Sultana DA, et al., Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development. Blood. 2009 Mar 26;113(13):2976-87
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3848126
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Gene symbol:
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Ptprc
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Gene name:
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protein tyrosine phosphatase receptor type C
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Results
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Specimen
1A:
embryonic day 11.5
(more  )
Specimen
1A:
(close  )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Specimen
5A +/+:
embryonic day 12.5
(more )
Specimen
5A +/+:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: thymus primordium |
Present |
Regionally restricted |
5A CD45 MafB+/+
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Expression was detected in lymphoid cells in the thymus.
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Specimen
5A +/-:
embryonic day 12.5; Mafbtm1Jeng/Mafb +
(more )
Specimen
5A +/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Mafbtm1Jeng/Mafb+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: thymus primordium |
Present |
Regionally restricted |
5A CD45 MafB+/-
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Expression was detected in lymphoid cells in the thymus. The number of cells in the heterozygous mice was approximately 75% of that of wild type mice.
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Specimen
5A -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Mafbtm1Jeng/Mafbtm1Jeng
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: thymus primordium |
Present |
Regionally restricted |
5A CD45 MafB-/-
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Expression was detected in lymphoid cells in the thymus. The number of cells in homozygous mutant mice was approximately half of that of wild type mice.
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Specimen
5B +/+:
embryonic day 13.5
(more )
Specimen
5B +/+:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: thymus primordium |
Present |
Regionally restricted |
5B CD45 MafB+/+
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Expression was detected in lymphoid cells in the thymus. The number of cells was 4-fold larger than in E12.5 wild type mice.
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Specimen
5B +/-:
embryonic day 13.5; Mafbtm1Jeng/Mafb +
(more )
Specimen
5B +/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Mafbtm1Jeng/Mafb+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: thymus primordium |
Present |
Regionally restricted |
5B CD45 MafB+/-
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Expression was detected in lymphoid cells in the thymus. The number of cells in the heterozygous mice was approximately 75% of that of wild type mice.
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Specimen
5B -/-:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6J
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Mutant Allele(s):
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Mafbtm1Jeng/Mafbtm1Jeng
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: thymus primordium |
Present |
Regionally restricted |
5B CD45 MafB-/-
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Expression was detected in lymphoid cells in the thymus. The number of cells in homozygous mutant mice was approximately half of that of wild type mice.
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Analysis Tools