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Gene Expression Data
Assay Details
Assay
Reference: J:136160 Joesting MS, et al., Secreted frizzled related protein 1 is a paracrine modulator of epithelial branching morphogenesis, proliferation, and secretory gene expression in the prostate. Dev Biol. 2008 May 1;317(1):161-73
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3846412
Gene symbol: Sfrp1
Gene name: secreted frizzled-related protein 1
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 8.0; Sfrp1tm1Jrbn/Sfrp1+ (more )
Note: 3 somite stage. The specimens were post-fixed in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS12: future spinal cord neural plate Weak 2A
TS12: yolk sac Weak 2A
Specimen 2B: embryonic day 8.5; Sfrp1tm1Jrbn/Sfrp1+ (more )
Note: 9 somite stage. The specimens were post-fixed in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS13: optic pit Strong Regionally restricted 2B Expression was strong in the ventral optic cup.
TS13: future hindbrain Strong 2B
TS13: future spinal cord Strong 2B
TS13: allantois Weak 2B
Specimen 2C: embryonic day 9.5; Sfrp1tm1Jrbn/Sfrp1+ (more )
Note: The specimens were post-fixed in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS15: central nervous system Strong Regionally restricted 2C Expression was localized primarily to the ventral regions.
TS15: future spinal cord Strong Regionally restricted 2C Expression was localized primarily to the ventral regions.
TS15: hindgut Strong Regionally restricted 2C Expression was localized primarily to the ventral regions.
TS15: eye Present 2C
TS15: future forebrain Present 2C
TS15: future midbrain Present 2C
TS15: trunk mesenchyme Strong Regionally restricted 2C Expression was detected in the lateral plate.
Specimen 2D: embryonic day 8.5; Sfrp1tm1Jrbn/Sfrp1+ (more )
Note: 9 somite stage. The specimens were post-fixed in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS13: future hindbrain Present Regionally restricted 2D Expression was detected in the ventral domains of the hindbrain.
Specimen 2E: postnatal day 21; Sfrp1tm1Jrbn/Sfrp1+ (more )
Structure Level Pattern Image Note
TS28: prostate gland Present Regionally restricted 2E Expression was detected in the developing mesenchyme/stroma.
TS28: prostate epithelium Absent 2E
Specimen Not Shown: postnatal day 1; Sfrp1tm1Jrbn/Sfrp1+ (more )
Structure Level Pattern Image Note
TS27: prostate bud Present Regionally restricted Expression was detected in the mesenchyme/stroma.
TS27: prostate epithelium Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory