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Gene Expression Data
Assay Details
Assay
Reference: J:14429 Thomas T, et al., Genes coding for basement membrane glycoproteins laminin, nidogen, and collagen IV are differentially expressed in the nervous system and by epithelial, endothelial, and mesenchymal cells of the mouse embryo. Exp Cell Res. 1993 Sep;208(1):54-67
Assay type: RNA in situ
MGI Accession ID: MGI:3845871
Gene symbol: Lamc1
Gene name: laminin, gamma 1
Probe: laminin B2 probe1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord ventricular layer Strong Regionally restricted 2C High levels of expression in the ventral portion of the ependymal zone cells.
TS20: embryo mesenchyme Present Regionally restricted 2C Expression in mesenchyme cells surrounding the central nervous system destined to become the meninges.
TS20: tail myocoele Trace 2C Expression was either very low or not detected.

Specimen 2G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: blood vessel Weak Regionally restricted 2G Expression in differentiating capillaries

Specimen 3B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord ventricular layer Present Regionally restricted 3B Expression in ependymal cells in the ventral region of the spinal cord.
TS20: spinal cord floor plate Present 3B
TS20: embryo mesenchyme Present Regionally restricted 3B Expression in the primitive meninges.
TS20: spinal cord mantle layer Absent 3B

Specimen 5C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo mesenchyme Strong Regionally restricted 5C High levels of expression in mesenchyme cells surrounding ganglia.
TS20: dorsal root ganglion Weak Regionally restricted 5C Low levels of expression in a subset of cells within the ganglia.
TS20: spinal nerve Strong 5C High levels of expression in ganglia fibers and associated nerve roots.
TS20: vertebral cartilage condensation Absent 5C No expression in neural arches.
TS20: tail myocoele Trace 5C Expression was either very low or not detected.

Specimen 6C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral region Absent 6C
TS20: tongue Weak Regionally restricted 6C Preferentially expressed in isolated groups of cells in the base of the tongue.

Specimen 7C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present 7C
TS20: endocardial lining Present 7C
TS20: heart atrium Present 7C
TS20: heart ventricle Present 7C

Specimen 8C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach epithelium Strong 8C Uniform high expression in epithelial cells and surrounding mesenchyme.
TS20: stomach mesenchyme Strong 8C Uniform high expression in epithelial cells and surrounding mesenchyme.
TS20: liver Present Regionally restricted 8C Lower levels of expression in groups of cells in the epithelium and througout the mesenchyme.

Specimen 9C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: metanephros Present Uniform 9C Uniform expression in both epithelial and mesenchymal compartments.
TS20: dorsal aorta Present 9C Expression in the aorta, essentially the same as in surrounding mesenchyme.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory