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Gene Expression Data
Assay Details
Assay
Reference: J:124356 Bondareva AA, et al., Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radic Biol Med. 2007 Sep 15;43(6):911-23
Assay type: RNA in situ
MGI Accession ID: MGI:3844849
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 cDNA21
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4 Fgf8 +/+: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: primitive streak Present 4_Fgf8 +/+
TS11: embryo endoderm Weak Regionally restricted 4_Fgf8 +/+ Expression is in the anterior endoderm.

Specimen 4 Fgf8 -/-: embryonic day 7.5; Txnrd1tm1.1Ees/Txnrd1tm1.1Ees (more )
Structure Level Pattern Image Note
TS11: embryo ectoderm Present Regionally restricted 4_Fgf8 -/- Expression is in the proximal embryonic ectoderm.
TS11: extraembryonic visceral endoderm Present Regionally restricted 4_Fgf8 -/- Expression is in the distal visceral endoderm.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory